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bioinfo2

Functional genomics

Microarrays

Microarray Bioinformatics at EBI
Arrayexpress at the EBI
Expression Profiler at EBI
Documentation for Expression Profiler
NCBI GEO Gene Expression Omnibus
Stanford Microarray Database
Microarray Gene Expression Data Society
Yale Microarray Database
TIGR functional genomics
NGFN German National Functional Genomics Network
Genevestigator
CATMA – A complete Arabidopsis Transcriptome MicroArray
The Arabidopsis Information Resource - TAIR
AFGN Arabidopsis Functional Genomics Network
Microarray.Org – Microarray protocols and software
NIH - Guide to Microarray Data analysis
Microarray Tools at NCI
Mesher - TIGR MeSH terms overrepresented in microarray data
J-Express microarray analysis free version
MicroArray Explorer tool for Data Mining Gene Expression Patterns
Cluster and Treeview from the Eisen Lab
BioConductor Project - Open Source Software for Bioinformatics
TIGR TM4 Microarray Software Suite
Broad Institute Genecluster 2.0
dChip Software: Gene Expression Microarray and SNP Microarray Analysis
NASC Affymetrix Service: Analysis hints
Analysis of Affymetrix data using Excel
Affymetrix - NetAffx™ Analysis Center
MapMan - integrative view of microarray data and metabolic maps
GenMAPP Gene Map Annotator and Pathway Profiler

Proteomics

EXPASY Swiss 2Dpage
WORLD-2DPAGE Index to 2D-PAGE databases and services
EXPASY Peptide Mass Tool
EXPASY Aldente Peptide Mass Fingerprinting Tool
MASCOT Peptide Mass Fingerprint
UCSF Protein Prospector
PROWL protein and MS tools
PRIDE - Proteomics Identifications Database
RESID Database of protein modifications
Scaffold protein identification framework (by Proteome Software)
Proteomics Society
HUPO - Human Proteome Organisation
HPI - Human Proteomics Initiative
gabi Arabidopsis Proteomics Data
Proteomics from Angelika Görg
Boston University Biology Proteomics Resource
Deutsche Gesellschaft für Proteomforschung
SWISS Proteomics Society Proteomics Links
IonSource Proteomics Resource Links

Protein-Protein Interactions

EBI IntAct Project
DIP - Database of Interacting Proteins
BOND - Biomolecular Object Network Databank
MIPS Mammalian Protein-Protein Interaction Database
BioGRID - General Repository for Interaction Datasets
HPID Human Protein Interaction Database
The JCB Protein-Protein Interaction Website
MIPS Yeast Protein-Protein-Interaction and Complex Viewer
Yeast Protein complex database
MINT - Molecular Interactions database
Complexpander - Predicting protein complexes
PathBlast - Comparison of interaction networks between organisms
iHOP - Information Hyperlinked over Proteins
String: functional protein association networks
PreBIND literature protein interaction extractor
BioPAX - data exchange for biologicaql pathway data
Graphviz - Open Source Graph Visualization Software
Cytoscape - open source software for interaction visualization and integration
visANT - Visual Analysis Tool for Biological Networks and Pathways
aiSee - commercial Graph layout software
Stratagene PathwayArchitect Software

miRNA

RNA Molecular Biology Tuschl Lab
miRBASE microRNA database Sanger Institute
Rfam RNA families database of alignments and CMs Sanger Institute
The siRNA user guide - Tuschl Lab

Systems Biology

System Biology Information Resources

The Systems Biology Institute - Tokyo
BioModels.NET
The Reactome Project
Panther Classification Systems - Panther Pathways
KDBI - Kinetic Data of Biomolecular Interactions
SBML Systems Biology Markup Language
Systems Biology at UC San Diego
The International Society for Systems Biology
Systems Biology Portal www.systems-biology.org
HepatoSys - Network Systems Biology
SystemsX - The Swiss Initiative in Systems Biology
YSBN The Yeast Systems Biology Network

Systems Biology Modeling Tools

Systems Biology WorkBench SWB package
JDesigner: A Biochemical Network Layout Tool
Jarnac biochemical simulation package
Pasadena Twain ODE solver of the SWB package
CADLIVE - network construction system
Dizzy stochastic simulations tool
CellDesigner - a modeling tool for biochemical networks
CellWare - building computational chassis for systems and synthetic biology
E-Cell project
COPASI - Complex Pathway Simulator
Gepasi - Biochemical Kinetics Simulator
Dynetica - a simulator of dynamic networks
PLAS Power Law Analysis and Simulation tool
JSim - a Java based simulation system
STOCKS - Stochastic kinetic simulations
Basis Gillespie Stochastic Simulator
CaliBayes - Bayesian calibration of biological simulators
JWS Online - Online Cellular Systems Modelling
PyBioS - web server for modeling and simulation of cellular systems
Virtual Cell Internet simulation server at NRCAM

Small molecules

KEGG Drug Database
KEGG Ligand Database
ChEBI - Chemical Entities of Biological Interest
MSD Ligand Chemistry in PDB
NCBI PubChem Compound
NCBI PubChem Substance
NLM SIS Chemical Information
NCI-3D Search
ChemIDplus
ChemFinder Searching
CHEMINFO: Chemical Information Sources from Indiana University
Acronymfinder

Annotation

Gene Function Resources

Gene Ontology (GO) Consortium
QuickGO - GO Browser at EBI
AmiGO - GO Browser
GOA - Gene Ontology Annotation Project at EBI
GOStat - find statistically overrepresented GO terms
Online Mendelian Inheritance in Man
GeneCards Weizmann
Genetic Association Database

Integrated annotation services

NIH - DAVID 2006 Annotation tools
eFamily Project - Grid integrating of protein database annotations
DAS - Distributed Annotation System
DAS registry server at Sanger - available DAS servers
SPICE - DAS Client
EnsEMBL Genome Browser DAS client
Dasty - DAS client

Gene prediction services

AAT Server - Analysis and Annotation Tool
Glimmer Microbial Gene-Finding System
GrailExp Grail Experimental Gene Discovery Suite
BCM Gene Feature Searches
CBS HMMgene server
CBS NetGene2 server
CBS NetPlantGene server
CBS Genome Atlas
GeneMark
WebGeneMark
Eukaryotic WebGeneMark
GENSCAN (C. Burge)
SplicePredictor
Lowe Lab tRNAscan-SE Search Server
Rat Genome Database METAGENE Annotation Tool

Promotor prediction services

CBS NetStart 1.0 server Translation Start
CBS Promoter 2.0 server
WWW Promotor Scan Pol II
EPD Eukaryotic promotor database
JASPAR Transcription factor binding profile database
TRADAT Transcription Databases and Analysis Tool
TFSEARCH - Transcription Factor Search
ORegAnno: Open Regulatory Annotation
cisRED: cis-regulatory element database
MotifMogul - Multiple Transcription Factor Bindin Sites Algorithms

Pathways

KEGG: Kyoto Encyclopedia of Genes and Genomes
ExPASy - Biochemical Pathways
BioCarta - Pathways
PANTHER (Protein ANalysis THrough Evolutionary Relationships) Classification System
Signaling Gateway - Cell Signaling Resource Nature
Reactome Project
Pathway Knowledge Base
BioCyc Database Collection
MetaCyc Encyclopedia of Metabolic Pathways
MIM Molecular Interaction Maps at NCI
IUPHAR receptor database
LGICD Ligand-gated ion-channel database
SPAD: Signaling PAthways Database
AraCyc - Pathway Database of Arabidopsis thaliana
DRASTIC- Database resource for analysis of signal transduction in plant cells
Invitrogen iPath Human Biological Pathways
BBID-Biological Biochemical Image Database
biodirectory - biochemical and metabolic pathways
Signal Transduction - Biochemweb.org virtual library
BioPAX - data exchange for biological pathway data
visANT - Visual Analysis Tool for Biological Networks and Pathways
MapMan - integrative view of microarray data and metabolic maps
GenMAPP Gene Map Annotator and Pathway Profiler

Enzymes

Enzyme Database - BRENDA
REBASE The Restriction Enzyme Database
PRIME Developed Kinase Pathway Database
Kinase.com Global kinome analysis
IntEnz EBI Enzyme Database
Catalytic Site Atlas - CSA (EBI)

Motifs Profiles Domains

Interpro Domain and Profile Database
ExPASy - PROSITE
ExPASy - ScanProsite tool
SIB myHits motif scan
PRINTS protein fingerprints
SMART - Simple Modular Architecture Research Tool
Blocks WWW Server
Block Search
The Sanger Centre Pfam Server
The Sanger Centre HMM Pfam Searcher
TIGRFAMs protein families HMM
ProDom conserved protein domains
CDD Conserved domains database NCBI
PANTHER (Protein ANalysis THrough Evolutionary Relationships) Classification System
PIR iProClass Protein Classification
Superfamily HMM models SCOP
Gene3D Structural and Functional Annotation
ModBase - Comparative protein structure models
WebLogo Server for Sequence Logos

Protein structures

RCSB Protein Data Bank
Entrez-Structure
MSD Macromolecular Structure Database at EBI
Structures by electron microscopy at MSD
SWISS-MODEL
EMBNet - A Quick Guide to Swiss-Model
SCOP: Structural Classification of Proteins
Superfamily HMM models SCOP
CATH database of structural domains
Gene3D Structural and Functional Annotation
The DALI database
Domain Structure Database NCBI
ModBase - Comparative protein structure models
BALL and BALLView Visualization and Modelling Tools

Sequences

Entrez Browser NCBI
SRSWWW EMBL-EBI
DBGET/LinkDB Integrated Database Retrieval System
SRSWWW at Expasy
BCM Search Launcher
GeneCards Weizmann
Genome Matrix databases information integration
RefSeq Reference Sequence NCBI
Unigene NCBI
Uniprot Universal Protein Resource Swiss-Prot/TREMBL/PIR
EMBNet QuickGuide Swissprot Trembl Databases
PIR - Protein Information Resource
IPI - International Protein Index EBI
Vector Database

Genomes

Ensembl Genome Browser
Entrez-Genome NCBI
Integr8 Proteome Analysis at EBI
GOLD: Genomes On Line Database v 2.0
CBS Genome atlas database
MIPS: Munich Information Centre for Protein Sequences
The Institute for Genomic Research
The Sanger Centre
Whitehead Institute
Broad Institute Center for Genome Research
GeneCards Weizmann
HGP - Human genome project information
DHGP - German human genome project
Human Genome Resources NCBI
Mouse Genome Resources NCBI
Rat Genome resources NCBI
Fugu Fish Genomics Project QMUL
ZFIN - Zebrafish information network
Wormbase C. elegans
C.elegans Blast server (Sanger Centre)
FlyBase Drosophila
Yeast Genome Database MIPS
Yeast Protein complex database
Schizosaccharomyces pombe genome (Sanger Centre)
Neurospora crassa Database (Broad)
Neurospora crassa Database (MIPS)
Fungal Genetics Stock Center
tair - The Arabidopsis Information Resource
GABI Primary Database ( GabiPD ) - Genomanalyse Pflanze
Plant genomes (MIPS)
Maize Genetics and Genomic Database
International Rice Genome Sequencing Project

Bioinformatics server

EBI European Bioinformatics Institute
NCBI US National Center for Biotechnology Information
GenomeNet WWW server Japan
Expasy Proteomics Server
EMBNet - A Quick Guide to Expasy
Pôle Bio-Informatique Lyonnais
Weizmann Institute Bioinformatics and Biological Computing
Baylor College of Medicine HGSC
San Diego Supercomputer Center Biological Projects
Bielefeld University Bioinformatics Server
HUSAR Bioinformatics Lab - Biocomputing Services at DKFZ
The Genomics and Bioinformatics Group NCI

The bioinformatics bench

Linux

Novell SUSE Linux
Linux Online
RedHat Linux
Debian Linux
Ubuntu Linux
Linux Kernel Archives
Knoppix
BioKnoppix
BioLinux
EMBNet A QuickGuide to UNIX
Linux Community (German)
linux.de
Linux user group Tuebingen

Apache and HTML

Apache
SELFHTML

MySQL

MySQL

PHP

PHP
SELFPHP
PHP FAQ
phpMyAdmin
php-homepage.de - Resource fuer PHP und MySQL
PHP-Archiv - PHP Scripts
phpwelt

Perl and R

PERL
The Perl directory at perl.org
Perl documentation
ActiveState - ActivePerl Downloads
CPAN PERL Script Archiv
Bioperl
EMBNet QickGuides PERL and Regular Expressions
BioConductor Project - Open Source Software for Bioinformatics
BioConductor Course CSAMA June 2007 Brixen
The R project for statistical computing
The Comprehensive R archive network
Open Source Initiative OSI
SourceForge.net Open Source Resource

Editors

The Vim Editor
Proton

Enote

DOE 2000 Electronic Notebook Project ORNL
DOE 2000 Electronic Notebook Project Main
WETLAB: an open source electronic lab notebook

EMBOSS

European Molecular Biology Open Software Suite EMBOSS
EMBNet Quick Guides EMBOSS and wEMBOSS
mEMBOSS for Microsoft Windows
Ready-to-install EMBOSS at BioLinux
wEMBOSS
BioKNOPPIX with JEMBOSS and EMBOSS
Bioinformatic System Management Workshop 2005

Open Source Bioinformatics Platforms

myGRID - Open Source Middleware Environment for Bioinformatics Workflows
TAVERNA Open Source Bioinformatics Workbench
eFamily Project - Grid integrating of protein database annotations
Bioclipse - visual platform for structural chemo- and bioinformatics
Systems Biology WorkBench SWB package
Bioinformatics Web APIs (nodalpoint wiki)