Bookmarks
bioinfo2
Functional genomics
Transcriptomics databases
- Microarray Bioinformatics at EBI
- Arrayexpress at the EBI
- Expression Profiler at EBI
- Documentation for Expression Profiler
- Gene Expression Atlas - Large Scale Meta-Analysis of Public Microarray Data
- GEO Gene Expression Omnibus at NCBI
- NCBI Sequence Read Archive
- MaRe Microarray Retriever
- Stanford Microarray Database
- Yale Microarray Database
- JCV Institute Genomics
- NIH ENCODE Project: ENCyclopedia Of DNA Elements
- NGFN German National Functional Genomics Network
- Genevestigator
- GeneCAT - Gene Co-expression Analysis Toolbox
- CATMA - A complete Arabidopsis Transcriptome MicroArray
- The Arabidopsis Information Resource - TAIR
- AFGN Arabidopsis Functional Genomics Network
- Microarray Gene Expression Data Society
- Stanford Functional Genomics Facility
Transcriptomics tools
- NIH - Guide to Microarray Data analysis
- Microarray Tools at NCI
- HSLS: Microarray, SAGE and other gene expression data analysis tools
- J-Express microarray analysis free version
- MicroArray Explorer tool for Data Mining Gene Expression Patterns
- Tools from the Eisen Lab
- BioConductor Project - Open Source Software for Bioinformatics
- R and Bioconductor Manual (Thomas Girke)
- Babelomics - Systems biology microarray data mining
- TIGR Microarray Software
- RNA-Seq software ERANGE
- Broad Institute Genecluster 2.0
- dChip Software: Gene Expression Microarray and SNP Microarray Analysis
- NASC Affymetrix Service: Analysis hints
- Analysis of Affymetrix data using Excel
- Affymetrix - NetAffx TM Analysis Center
- MapMan - integrative view of microarray data and metabolic maps
- GenMAPP Gene Map Annotator and Pathway Profiler
Proteomics databases and search engines
- ExPASy Swiss 2Dpage
- WORLD-2DPAGE Index to 2D-PAGE databases and services
- ExPASy Peptide Mass Tool
- ExPASy Mass Search
- ExPASy MultIdent Peptide Mass Fingerprinting Tool
- MASCOT Peptide Mass Fingerprint
- SEQUEST MS proteomics search engine
- Phenyx MS protein search engine (GeneBio/SIB)
- X! Tandem MS search engine
- OMSSA ms/ms search engine
- UCSF Mass Spectrometry Facility Protein Prospector
- PROWL protein and MS tools
- PRIDE - Proteomics Identifications Database
- PeptideAtlas
- GPMDB proteomics database
- Human Protein Atlas
- Tranche - Secure P2P for Scientific Data Dissemination
- ISPIDER MS meta protein database search
- Protein Identifier Cross-Reference Service
- NIH Histone Sequence Database
- Phospho.ELM Database of phosphorylation sites
- PhosphoPep Phosphopeptide systems biology database
- Human Protein Reference Database
Proteomics post translational modifications
- ExPASy - FindMod tool
- ExPASy - QuickMod - MS/MS modified peptide search tool
- RESID Database of protein modifications
- Delta Mass PTM database (ABFR)
- Unimod database - protein modifications for MS
- Unimod - Modification naming guidelines
- PRIDE Modification Search
- PRIDE modification ontology lookup service (OLS)
- ExPASy - Sulfinator tool Tyr sulfination sites predictor
- NetPhos 2.0 Server STY phosphorylation site predictor
- HUPO PSI Protein Modification Documentation
Proteomics software
- TPP Trans-Proteomic Pipeline
- SASHIMI MS proteomics pipeline
- OpenMS / TOPP open source MS proteomics pipeline
- MaxQuant
- ICPLQuant
- Scaffold protein identification framework (by Proteome Software)
- mMass - Open Source Mass Spectrometry Tool
- PeptideProphet MS proteomics prediction tool
- ProteinProphet MS proteomics prediction tool
- MassTRIX Metabolomics mass to pathway mapper
Proteomics organisations and standards
- HUPO - Human Proteome Organisation
- UniProt Chordata protein annotation program
- HUPO Proteomics Standards Initiative
- MASC Arabidopsis Proteomics Standards Subcommittee
- mzML Specification | HUPO Proteomics Standards Initiative
- Mass spectrometry data formats - Wikipedia
- gabi Arabidopsis Proteomics Data
- Proteomics from Angelika Görg
- Boston University Biology Proteomics Resource
- Deutsche Gesellschaft für Proteomforschung
- Swiss Proteomics Society
- SWISS Proteomics Society Proteomics Links
- Proteome commons
- ISB NHLBI Seattle Proteome Center
- IonSource Proteomics Resource Links
Protein-Protein Interactions
- EBI IntAct Project
- DIP - Database of Interacting Proteins
- DIP DLRP Database of Interactiong Proteins
- BOND - Biomolecular Object Network Database
- BioGRID - General Repository for Interaction Datasets
- MINT - Molecular Interactions database
- GNP Genome Network Platform
- MIPS MPact Protein Interaction and Complex DB
- MIPS Mammalian Protein-Protein Interaction Databank
- The JCB Protein-Protein Interaction Website
- GeneInfinity's Protein Interaction Analysis page
- HPRD Human Protein Reference Database
- Human Protein Interaction Database
- NCBI HIV Human protein interaction database
- UniHI MDC Unified Human Interactome
- MIPS Yeast Protein-Protein-Interaction and Complex Viewer
- Yeast Protein complex database
- HomoMINT predicted human interaction network
- PIPs Human Protein Interaction Prediction Database
- Domino Domain peptide interaction database
- VirusMINT
- OPHID Interologous interaction database
- PathBlast - Comparison of interaction networks between organisms
- iHOP - Information Hyperlinked over Proteins
- String: functional protein association networks
- 3DID - 3D interacting domains
- DOMINE Database of Protein Domain Interactions
- PSI-MI HUPO Standard for interactions
- BioPAX - data exchange for biologicaql pathway data
- Graphviz - Open Source Graph Visualization Software
- Cytoscape - open source software for interaction visualization and integration
- Osprey - protein interaction viewer
- Osprey - protein interaction molecular modeling
- visANT - Visual Analysis Tool for Biological Networks and Pathways
- aiSee - commercial Graph layout software
- NAViGaTOR - Network Analysis, Visualization, & Graphing TORonto
miRNA
- RNA Molecular Biology Tuschl Lab
- miRBASE microRNA database Sanger Institute
- Rfam RNA families database of alignments and CMs Sanger Institute
- The siRNA user guide - Tuschl Lab
- microRNA.org: A resource for predicted microRNA targets and expression
- OligoWalk Web Server for siRNA design
- AsiDesigner siRNA design pipeline
Systems Biology
System Biology Information Resources
- BioModels.NET
- The Reactome Project
- Panther Classification Systems - Panther Pathways
- Human Metabolome Database
- KDBI - Kinetic Data of Biomolecular Interactions
- SBML Systems Biology Markup Language
- SBGN Systems Biology Graphical Notation Standardization
- The International Society for Systems Biology
- Systems Biology Portal www.systems-biology.org
- The Systems Biology Institute - Tokyo
- US National Centers for System Biology
- Systems Biology at UC San Diego
- Systems Biology in Germany
- HepatoSys - Network Systems Biology
- SystemsX - The Swiss Initiative in Systems Biology
- YSBN The Yeast Systems Biology Network
- Nature web focus: Systems biology: a user's guide
- Systems Biology Wikipedia
Systems Biology Modeling Tools
- Systems Biology WorkBench SBW package
- JDesigner: A Biochemical Network Layout Tool
- Jarnac biochemical simulation package
- Pasadena Twain ODE solver of the SWB package
- CADLIVE - network construction system
- Dizzy stochastic simulations tool
- CellDesigner - a modeling tool for biochemical networks
- SBMLsqueezer: A CellDesigner plug-in to generate kinetic rate equations for biochemical networks
- Cellware - Modeling and Simulation Tool
- E-Cell project
- COPASI - Complex Pathway Simulator
- Gepasi - Biochemical Kinetics Simulator
- Dynetica - a simulator of dynamic networks
- JSim - a Java based simulation system
- STOCKS - Stochastic kinetic simulations
- Basis Gillespie Stochastic Simulator
- CaliBayes - Bayesian calibration of biological simulators
- JWS Online - Online Cellular Systems Modelling
- PyBioS - web server for modeling and simulation of cellular systems
- Virtual Cell Internet simulation server at NRCAM
Small molecules
- Human Metabolome Database
- KEGG Drug Database
- KEGG Ligand Database
- ChEBI - Chemical Entities of Biological Interest
- MSD Ligand Chemistry in PDB
- NCBI PubChem Compound
- NCBI PubChem Substance
- NLM SIS Chemical Information
- NCI-3D Search
- ChemIDplus
- CHEMINFO: Chemical Information Sources from Indiana University
- FAF-Drugs: Free ADME/tox Filtering
- OpenBabel format conversion tool for drugs
- Java Molecular Editor at RPBS
- JME Molecular Editor by Peter Ertl
- SuperPred Drug Target Prediction Server
Annotation
Gene Function Resources
- Gene Ontology (GO) Consortium
- QuickGO - GO Browser at EBI
- AmiGO - GO Browser
- Ontology Lookup Service (OLS)
- GOA - Gene Ontology Annotation Project at EBI
- GOStat - find statistically overrepresented GO terms
- Gene Ontology Tools for Gene Expression Analysis
- Sequence Ontology Project
- Online Mendelian Inheritance in Man
- GeneCards Weizmann
- Genetic Association Database
Integrated annotation services
- NIH - DAVID Annotation tools
- eFamily Project - Grid integrating of protein database annotations
- DAS - Distributed Annotation System
- DAS registry server at Sanger - available DAS servers
- SPICE - DAS Client
- EnsEMBL Genome Browser DAS client
- Dasty - DAS client
Gene prediction services
- Glimmer Microbial Gene-Finding System
- NCBI Glimmer3
- GrailExp Grail Experimental Gene Discovery Suite
- BCM Gene Feature Searches
- CBS HMMgene server
- CBS NetGene2 server
- CBS NetPlantGene server
- CBS Genome Atlas
- GeneMark
- WebGeneMark
- Eukaryotic WebGeneMark
- GENSCAN (C. Burge)
- SplicePredictor
- ESTScan: a program for detecting, evaluating, and reconstructing potential coding regions in EST sequences
- EBI Wise2 matches protein to genomic DNA
- Lowe Lab tRNAscan-SE Search Server
Promotor prediction services
- CBS NetStart 1.0 server Translation Start
- CBS Promoter 2.0 server
- WWW Promotor Scan Pol II
- EPD Eukaryotic promotor database
- TFM Explorer
- TFM-Scan
- TFSEARCH - Transcription Factor Search
- TRANSFAC database at Biobase Biological Databases
- ORegAnno: Open Regulatory Annotation
- JASPAR Transcription factor database
- JASPAR Transcription factor database paper
- MotifMogul - Multiple Transcription Factor Binding Sites Algorithms
- Regulatory Sequence Analysis Tools (RSAT)
- DIALIGN - multiple sequence alignments to find conserved regulatory elements
- The Gibbs Motif Sampler
- MEME MAST motif discovery and search
- DiRE identification of DIstant Regulatory Elements of co-regulated genes
- ConTra - identification of conserved transcription factor binding sites
Databases
Pathways
- KEGG: Kyoto Encyclopedia of Genes and Genomes
- ExPASy - Biochemical Pathways
- NCI BioCarta - Pathways
- PANTHER (Protein ANalysis THrough Evolutionary Relationships) Classification System
- Signaling Gateway - Cell Signaling Resource Nature
- Reactome Project
- BioCyc Database Collection
- MetaCyc Encyclopedia of Metabolic Pathways
- NCI Nature Pathway Interaction Database
- IUPHAR receptor database
- LGICD Ligand-gated ion-channel database
- AraCyc - Pathway Database of Arabidopsis thaliana
- Invitrogen Pathways
- NetPath human signal transduction pathways
- BBID-Biological Biochemical Image Database
- Signal Transduction - Biochemweb.org virtual library
- BioPAX - data exchange for biological pathway data
- visANT - Visual Analysis Tool for Biological Networks and Pathways
- MapMan - integrative view of microarray data and metabolic maps
- GenMAPP Gene Map Annotator and Pathway Profiler
- Biological Networks
- Comparative Pathway Analyzer
- PaLS Pathway and Literature Strainer (gene set annotation tool)
- ProdoNet Prokaryotic gene list pathway annotator
- GraphWeb: analysis of biological networks
- Network Analysis Tools (NeAT)
Enzymes
- Enzyme Database - BRENDA
- IntEnz EBI Enzyme Database
- Catalytic Site Atlas - CSA (EBI)
- REBASE The Restriction Enzyme Database
- Protein Kinase Resource
- Kinase.com Global kinome analysis
- NetworKIN kinase substrate relationship prediction
Motifs Profiles Domains
- Interpro Domain and Profile Database
- ExPASy - PROSITE
- ExPASy - ScanProsite tool
- SIB myHits motif scan
- PRINTS protein fingerprints
- SMART - Simple Modular Architecture Research Tool
- Blocks WWW Server
- Block Search
- The Sanger Centre Pfam Server
- The Sanger Centre HMM Pfam Searcher
- TIGRFAMs protein families HMM
- ProDom conserved protein domains
- CDD Conserved domains database NCBI
- DomCut prediction of linker regions between functional domains
- PANTHER (Protein ANalysis THrough Evolutionary Relationships) Classification System
- PIR iProClass Protein Classification
- Superfamily HMM models SCOP
- Gene3D Structural and Functional Annotation
- ModBase - Comparative protein structure models
- Interproscan
- WebLogo
- WebLogo Server
- Human Protein Reference Database
- PhosphoMotif Finder
- ELM Eukaryotic Linear Motif Functional Site Prediction
- Phospho.ELM Database of phosphorylation sites
- NetworKIN kinase substrate relationship prediction
- DIALIGN - multiple sequence alignments to find conserved regulatory elements
- The Gibbs Motif Sampler
- MEME MAST motif discovery and search
Protein structures
- RCSB Protein Data Bank
- Entrez-Structure
- Conserved Domains Database NCBI
- Protein Databank in Europe (PDBe)
- Structures by electron microscopy at MSD
- SWISS-MODEL
- EMBNet - A Quick Guide to Swiss-Model
- SCOP: Structural Classification of Proteins
- Superfamily HMM models SCOP
- CATH database of structural domains
- Gene3D Structural and Functional Annotation
- The DALI database
- NCBI VAST structural alignments
- ModBase - Comparative protein structure models
- BALL and BALLView Visualization and Modelling Tools
Sequences
- Entrez Browser NCBI
- SRSWWW EMBL-EBI
- DBGET/LinkDB Integrated Database Retrieval System
- BCM Search Launcher
- GeneCards Weizmann
- Genome Matrix databases information integration
- RefSeq Reference Sequence NCBI
- Unigene NCBI
- Uniprot Universal Protein Resource Swiss-Prot/TREMBL/PIR
- EMBNet QuickGuide Swissprot Trembl Databases
- PIR - Protein Information Resource
- IPI - International Protein Index EBI
- Human Gene and Protein Database (HGPD)
- Protein Identifier Cross-Reference Service
- NCBI UniVec and VecScreen Vector contamination search
Genomes
- Ensembl Genome Browser
- Entrez-Genome NCBI
- Integr8 Proteome Analysis at EBI
- GOLD: Genomes On Line Database v 3.0
- CBS Genome atlas database
- MIPS: Munich Information Centre for Protein Sequences
- J. Craig Venter Institute (ex TIGR) MD USA
- The Sanger Centre
- Whitehead Institute
- Broad Institute Center for Genome Research
- GeneCards Weizmann
- HGP - Human genome project information
- Human Genome Resources NCBI
- Mouse Genome Resources NCBI
- Rat Genome resources NCBI
- Fugu Fish Genome Project
- ZFIN - Zebrafish information network
- Wormbase C. elegans
- C.elegans Blast server (Sanger Centre)
- FlyBase Drosophila
- Yeast Genome Database MIPS
- Schizosaccharomyces pombe genome (Sanger Centre)
- Neurospora crassa Database (Broad)
- Neurospora crassa Database (MIPS)
- Fungal Genetics Stock Center
- tair - The Arabidopsis Information Resource
- GABI Primary Database ( GabiPD ) - Genomanalyse Pflanze
- Plant genomes (MIPS)
- Maize Genetics and Genomic Database
- International Rice Genome Sequencing Project
- Potato Genome Sequencing Consortium
Bioinformatics server
- EBI European Bioinformatics Institute
- NCBI US National Center for Biotechnology Information
- GenomeNet WWW server Japan
- Expasy Proteomics Server
- EMBNet - A Quick Guide to Expasy
- Pôle Bio-Informatique Lyonnais
- Weizmann Institute Bioinformatics and Biological Computing
- Baylor College of Medicine HGSC
- Bioinformatics Software Server Lille
Link lists
- Expasy
- Expasy Life Science Directory
- Bioinformatics Links Directory UBiC
- HSLS: OBRC: Online Bioinformatics Resources Collection
- Nucleic Acids Research Database Summary Paper List
- Nucleic Acids Research Database Issue 2011
- Nucleic Acids Research Database Issue 2010
- Nucleic Acids Research Webserver Issue 2011
- Nucleic Acids Research Webserver Issue 2010
- CMS Molecular Biology Resource
- Harvard Dept of MCB - Biology Links
- CiteULike - online reference management sharing service
- Connotea - online reference and link sharing
- del.icio.us social bookmarking
- Biotech Europe Link Base
The bioinformatics bench
Linux
- Ubuntu Linux
- Debian Linux
- Open SUSE Linux
- Professional SUSE Linux
- Fedora Project
- RedHat Linux
- Linux Kernel Archives
- BioLinux - Wikipedia
- Knoppix
- BioKnoppix
- EMBNet A QuickGuide to UNIX
- Linux Community (German)
- linux.de
WAMP
- Apache
- SELFHTML
- MySQL
- PHP
- SELFPHP
- phpMyAdmin
- Comparison of WAMPs
- XAMPP
Perl
- Perl
- The Perl directory at perl.org
- Perl documentation
- Perl Download
- ActiveState - ActivePerl Downloads
- Strawberry Perl for Windows
- CPAN PERL Script Archiv
- Bioperl
- Installing Bioperl on Windows - BioPerl
- EMBNet QickGuides PERL and Regular Expressions
R and BioConductor
- The R project for statistical computing
- The Comprehensive R archive network
- BioConductor Project - Open Source Software for Bioinformatics
- R and Bioconductor Manual (Thomas Girke)
- useR! 2011 R user conference Warwick, UK
- useR! 2010 R user conference Gaithersburg, Maryland
Editors
- The Vim Editor
- Proton
- Komodo
Laboratory tools
- WETLAB: an open source electronic lab notebook
- PHP Labware Project
- OpenFreezer
EMBOSS
- EMBOSS
- EMBOSS wiki
- EMBOSS application wiki
- EMBOSS applications
- EMBOSS applications program groups
- EMBOSS for Windows
- EMBOSS Users Guide
- EMBOSS Developers Guide
- EMBOSS Administrators Guide
- EMBOSS user documentation
- EMBOSS FAQ
- EMBOSS Main Tutorial
- EMBOSS mailing lists
- EmbNet EMBOSS and wEMBOSS Quick Guides
- JEMBOSS
- wEMBOSS
- Public SRS installations | Biowisdom
NCBI BLAST software
- BLAST Wikipedia
- BLAST setup procedure for Windows
- NCBI BLAST download
- BLAST FASTA databases download
- BLAST standalone documentation
Open Source Bioinformatics Platforms
- Galaxy bioinformatics framework
- myGRID - Open Source Middleware Environment for Bioinformatics Workflows
- TAVERNA Open Source Bioinformatics Workbench
- eFamily Project - Grid integrating of protein database annotations
- Bioclipse - visual platform for structural chemo- and bioinformatics
- Systems Biology WorkBench SWB package
- Mobyle web environment for bioinformatics workflows
- Chinook P2P Bioinformatics Platform
- Gaggle data management framework