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Bioinfo1

Courses and lectures

Bioinformatics - Online Courses and Tutorials
The European School In Bioinformatics (Biosapiens)
4ESB The Fourth Biosapiens Eurropean School in Bioinformatics
VSNS Biocomputing Division
EMBNet Quick Guides
EMBNet Courses
EMBNet Biocomputing Tutorials - Introduction
Sequence Analysis with distributed Resources
BioComputing Hypertext Coursebook
Tutorial Protein Structures (EXPASY) SwissModel
CMBI Course Homology Modelling
BioInformatics Glossary

Organizations Conferences

Bioinformatik.de
Bioinformatics.Org - The Open-Access Institute
EMBNet Bioinformatics Network
Gesellschaft fuer Informatik - Fachgruppe Bioinformatik
GBM Gesellschaft fuer Biochemie und Molekularbiologie
ISCB - International Society for Computational Biology
GCB 2006 German Conference on Bioinformatics - Tuebingen
SBMC Conference on Systems Biology of Mammalian Cells 2006

Journals

Applied Bioinformatics
Bioinformatics
BioMed Central Bioinformatics
In Silico Biology
Nucleic Acids Research
Omics: A Journal of Integrative Biology
PLoS Computational Biology
Nature Omics Gateway
Proteomics
Electrophoresis
BioMed Central - Systems Biology Gateway
Molecular Systems Biology
BioSystems

Bioinformatics server

EBI European Bioinformatics Institute
NCBI US National Center for Biotechnology Information
GenomeNet WWW server Japan
Expasy Proteomics Server
EMBNet - A Quick Guide to Expasy
Pôle Bio-Informatique Lyonnais
Weizmann Institute Bioinformatics and Biological Computing
Baylor College of Medicine HGSC

Databases

Sequences

Entrez Browser NCBI
SRSWWW EMBL-EBI
DBGET/LinkDB Integrated Database Retrieval System
SRSWWW at Expasy
BCM Search Launcher
GeneCards Weizmann
Genome Matrix databases information integration
RefSeq Reference Sequence NCBI
Unigene NCBI
Uniprot Universal Protein Resource Swiss-Prot/TREMBL/PIR
EMBNet QuickGuide Swissprot Trembl Databases
PIR - Protein Information Resource
IPI - International Protein Index EBI

Genomes

Ensembl Genome Browser
Entrez-Genome NCBI
Integr8 Proteome Analysis at EBI
GOLD: Genomes On Line Database v 2.0
CBS Genome atlas database
MIPS: Munich Information Centre for Protein Sequences
The Institute for Genomic Research
The Sanger Centre
Broad Institute Center for Genome Research
HGP - Human genome project information
DHGP - German human genome project
Human Genome Resources NCBI
Mouse Genome Resources NCBI
Rat Genome resources NCBI
Fugu Fish Genomics Project QMUL
ZFIN - Zebrafish information network
Wormbase C. elegans
FlyBase Drosophila
Yeast Genome Database MIPS
tair - The Arabidopsis Information Resource
GABI Primary Database ( GabiPD ) - Genomanalyse Pflanze
Plant genomes (MIPS)

Protein structures

RCSB Protein Data Bank
Entrez-Structure
MSD Macromolecular Structure Database at EBI
SWISS-MODEL
EMBNet - A Quick Guide to Swiss-Model
SCOP: Structural Classification of Proteins
CATH database of structural domains
Gene3D Structural and Functional Annotation
The DALI database
Domain Structure Database NCBI
ModBase - Comparative protein structure models

Motifs Profiles Domains

Interpro Domain and Profile Database
ExPASy - PROSITE
ExPASy - ScanProsite tool
SIB myHits motif scan
PRINTS protein fingerprints
SMART - Simple Modular Architecture Research Tool
Blocks WWW Server
The Sanger Centre Pfam Server
ProDom conserved protein domains
CDD Conserved domains database NCBI
PIR iProClass Protein Classification
Superfamily HMM models SCOP
Gene3D Structural and Functional Annotation

Pathways

KEGG: Kyoto Encyclopedia of Genes and Genomes
ExPASy - Biochemical Pathways
BioCarta - Pathways
PANTHER (Protein ANalysis THrough Evolutionary Relationships) Classification System
Reactome Project
Pathway Knowledge Base
BioCyc Database Collection
MetaCyc Encyclopedia of Metabolic Pathways
IUPHAR receptor database
LGICD Ligand-gated ion-channel database
AraCyc - Pathway Database of Arabidopsis thaliana
Invitrogen iPath Human Biological Pathways
biodirectory - biochemical and metabolic pathways
Signal Transduction - Biochemweb.org virtual library
MapMan - integrative view of microarray data and metabolic maps
GenMAPP Gene Map Annotator and Pathway Profiler

Enzymes

Enzyme Database - BRENDA
REBASE The Restriction Enzyme Database
Protein Kinase Resource
Kinase.com Global kinome analysis
IntEnz EBI Enzyme Database
Catalytic Site Atlas - CSA (EBI)

Software

EBI: The BioCatalog
Bioperl
Open Source Initiative OSI
SourceForge.net Open Source Resource

Literature

Pub Med Central
Advanced PubMed Search
PubMed/Medline NLM Mesh Browser
PubMed Single Citation Matcher
NCBI Journal database
Scopus
Web of Science
Google Scholar
Scirus
Espacenet - Europe's network of patent databases
REDI Databases of Baden-Wuerttemberg
DOAJ - Directory of open access journals
PLoS Public Library of Science
WorldSciNet Search Engine - World Scientific
Crossref Search - commercial publishers worldwide common paper service

Information retrieval and clustering

EBIMed Medline information retrieval and extraction
GoPubMed - Ontology based literature search
HubMed pubmed rewired
MyNCBI PubMed updating and alerting
BioMail Pubmed Mail Update Service
PubCrawler PubMed GenBank Update Service
PubFinder - finds related articles in PubMed
eTBlast - related articles to any text
MedBlast - sequence-based literature retrieval
CoPub Mapper Gene Co-Publication Text Mining
PubMatrix
Vivisimo PubMed Clustering Search

Internet search

Search engines

Google
Clusty the Clustering Engine
AltaVista
Yahoo!
WebCrawler
MetaGer
CUSI - Suchmoeglichkeiten im Internet
W3 Search Engines FU Berlin

Link lists

Expasy
Expasy Life Science Directory
Bioinformatics Links Directory UBiC
Nucleic Acids Research Database Summary Paper List
Nucleic Acids Research Database Issue 2006
Nucleic Acids Research Webserver Issue 2006
CMS Molecular Biology Resource
Harvard Dept of MCB - Biology Links
Institute Pasteur Bio NetBook
CiteULike - online reference management sharing service
Connotea - online reference and link sharing

The bioinformatics bench

Linux

Novell SUSE Linux
Linux Online
RedHat Linux
Debian Linux
Ubuntu Linux
Linux Kernel Archives
Knoppix
BioKnoppix
BioLinux
EMBNet A QuickGuide to UNIX
Linux Community (German)
linux.de
Linux user group Tuebingen

WAMP

Apache
SELFHTML
MySQL
PHP
SELFPHP
phpMyAdmin

Perl and R

PERL
The Perl directory at perl.org
Perl documentation
ActiveState - ActivePerl Downloads
CPAN PERL Script Archiv
Bioperl
BioConductor Project - Open Source Software for Bioinformatics
EMBNet QickGuides PERL and Regular Expressions
The R project for statistical computing
The Comprehensive R archive network

Editors

The Vim Editor
Proton

EMBOSS

European Molecular Biology Open Software Suite EMBOSS
EMBNet Quick Guides EMBOSS and wEMBOSS
Ready-to-install EMBOSS at BioLinux
wEMBOSS
BioKNOPPIX with JEMBOSS and EMBOSS
Bioinformatic System Management Workshop 2005

Alignment

WWW BLAST Database Searches at NCBI
EMBNet QuickGuide BLAST
Fasta3 Database Searches at the EBI
BCM Search Launcher: Multiple Sequence Alignments
The Sequence and Structure Searching Site Berkeley
PeCoP Psi-Blast to find persistently conserved positions
Directory of /pub/ClustalX
GeneDoc Homepage
ReadSeq

Sequence tools

BCM Sequence Utilities
SeWeR - Sequence Analysis using Web Resources
ReadSeq
Webcutter 2.0
Reverse Complement of Sequence
Primer 3
PrimerX - mutagenic primer design
pDraw32 (Acaclone) Plasmid drawing
Savvy Plasmid Maps
European Molecular Biology Open Software Suite EMBOSS

Protein tools

NPS: Network Protein Sequence Analysis
pI/Mw tool - Expasy
PeptideMass - Expasy
ProtParam tool - Expasy
ProtScale - Expasy
ISREC SAPS server

Phylogenetics

PHYLIP
BIOBOX / Phylip Online Server
Phylip Online Help
EMBNet A Quick Guide to PHYLIP
PAUP
TreeView
PANDIT Protein and Associated NucleotideDomains with Inferred Trees
PeCoP Psi-Blast to find persistently conserved positions
PHYLIP Phylogeny Programs
Phylogenetics Resources Berkeley
The Tree of Life Home Page
Tree of Life Links
NCBI Taxonomy Browser
The Mathematical Basis of Molecular Phylogenetics

Structures

Transmembrane features

TMHMM Server 2.0
ISREC TMpred Server
SOSUI Structure prediction of membrane proteins
HMMTOP Prediction of transmembrane helices and topology
TMAP multiple sequence alignment protein prediction
TMPred - Prediction of transmembrane regions and orientation
TopPred - Topology prediction of membrane helices

3D structures

RCSB PDB Protein Data Bank - PDB
NCBI Structure
MSD Macromolecular Structure Database at EBI
Domain Structure Database NCBI
NCBI VAST structural alignments
SWISS-MODEL
EMBNet - A Quick Guide to Swiss-Model
EMBL Dali protein structure comparison server
The DALI database Dali Fold Classification
GENO3D : Automatic Modeling of Protein Structure
CPHmodels - Homology modeling
ModBase - Comparative protein structure models
SCOP: Structural Classification of Proteins
Superfamily HMM models SCOP
CATH Protein Structure Classification Database
Gene3D Structural and Functional Annotation
PredictProtein
Cn3D Home Page
BALL and BALLView Visualization and Modelling Tools
DeepView Swiss-PdbViewer
Protein Explorer
RasMol
RasTop - Rasmol Graphical Interface
Chime
Principals of protein structure
Genetic algorithms on proteins

Signal peptides and glycosylation sites

SignalP server
PSORT WWW Server
WWW Signal Scan
NetOGlyc server
ExPASy - ScanProsite tool

Secondary structures

NNPredict
PredictProtein
PredictProtein Help
JPRED Secondary structure prediction
JUFO neuronal network prediction server
PSIPRED Protein Structure Prediction Server
NIH: GOR4 secondary structure prediction
PROF - Secondary Structure Prediction System
ISREC COILS Server
NPS: Consensus secondary structure prediction
NPS : coiled-coils prediction
NPS: MLRC
NPS: HNN
NPS: SOPMA
NPS: GOR4

RNA

BiC RNA folding services
Vienna RNA secondary structure servers

Small molecules

KEGG Drug Database
KEGG Ligand Database
ChEBI - Chemical Entities of Biological Interest
MSD Ligand Chemistry in PDB
NCBI PubChem Compound
NCBI PubChem Substance
NLM SIS Chemical Information

Annotation

Gene Function Resources

Gene Ontology (GO) Consortium
QuickGO - GO Browser at EBI
AmiGO - GO Browser
GOA - Gene Ontology Annotation Project at EBI
GOStat - find statistically overrepresented GO terms
Online Mendelian Inheritance in Man
GeneCards Weizmann

Integrated annotation services

DAS - Distributed Annotation System
DAS registry server at Sanger - available DAS servers
SPICE - DAS Client
EnsEMBL Genome Browser DAS client
Dasty - DAS client

Gene prediction services

AAT Server - Analysis and Annotation Tool
Glimmer Microbial Gene-Finding System
GrailExp Grail Experimental Gene Discovery Suite
BCM Gene Feature Searches
CBS HMMgene server
CBS NetGene2 server
CBS NetPlantGene server
CBS Genome Atlas
GeneMark
GENSCAN (C. Burge)
SplicePredictor
Lowe Lab tRNAscan-SE Search Server

Promotor prediction services

CBS NetStart 1.0 server Translation Start
CBS Promoter 2.0 server
WWW Promotor Scan Pol II
EPD Eukaryotic promotor database
TRADAT Transcription Databases and Analysis Tool
TFSEARCH - Transcription Factor Search
ORegAnno: Open Regulatory Annotation
cisRED: cis-regulatory element database

Functional genomics

Microarrays

Microarray Bioinformatics at EBI
Arrayexpress at the EBI
Expression Profiler at EBI
Documentation for Expression Profiler
GEO Gene Expression Omnibus at NCBI
Stanford Microarray Database
TIGR functional genomics
NGFN German National Functional Genomics Network
Genevestigator
The Arabidopsis Information Resource - TAIR
AFGN Arabidopsis Functional Genomics Network
Microarray Gene Expression Data Society
Microarray.Org - Microarray protocols and software
NIH - Guide to Microarray Data analysis
Microarray Tools at NCI
Mesher - TIGR MeSH terms overrepresented in microarray data
J-Express microarray analysis free version
MicroArray Explorer tool for Data Mining Gene Expression Patterns
Cluster and Treeview from the Eisen Lab
BioConductor Project - Open Source Software for Bioinformatics
TIGR TM4 Microarray Software Suite
Broad Institute Genecluster 2.0
dChip Software: Gene Expression Microarray and SNP Microarray Analysis
NASC Affymetrix Service: Analysis hints
Analysis of Affymetrix data using Excel
Affymetrix - NetAffx™ Analysis Center
MapMan - integrative view of microarray data and metabolic maps
GenMAPP Gene Map Annotator and Pathway Profiler

Proteomics

EXPASY Swiss 2Dpage
WORLD-2DPAGE Index to 2D-PAGE databases and services
EXPASY Peptide Mass Tool
EXPASY PeptIdent Tool
MASCOT Peptide Mass Fingerprint
UCSF Protein Prospector
PROWL protein and MS tools
RESID Database of protein modifications
HUPO - Human Proteome Organisation
HPI - Human Proteomics Initiative
gabi Arabidopsis Proteomics Data
Proteomics from Angelika Görg
Boston University Biology Proteomics Resource
Deutsche Gesellschaft für Proteomforschung
SWISS Proteomics Society Proteomics Links
IonSource Proteomics Resource Links

Protein-Protein Interactions

EBI IntAct Project
DIP - Database of Interacting Proteins
BOND - Biomolecular Object Network Databank
MIPS Mammalian Protein-Protein Interaction Database
BioGRID - General Repository for Interaction Datasets
HPID Human Protein Interaction Database
The JCB Protein-Protein Interaction Website
MIPS Yeast Protein-Protein-Interaction and Complex Viewer
Yeast Protein complex database
MINT - Molecular Interactions database
Complexpander - Predicting protein complexes
PathBlast - Comparison of interaction networks between organisms
iHOP - Information Hyperlinked over Proteins
String: functional protein association networks
SPIES - Scientific-literature-based protein interaction extraction system
Graphviz - Open Source Graph Visualization Software
Cytoscape - open source software for interaction visualization and integration

miRNA

RNA Molecular Biology Tuschl Lab
miRBASE microRNA database Sanger Institute
Rfam RNA families database of alignments and CMs Sanger Institute
The siRNA user guide - Tuschl Lab

Systems Biology

System Biology Information Resources

BioModels.NET
The Reactome Project
Panther Classification Systems - Panther Pathways
KDBI - Kinetic Data of Biomolecular Interactions
SBML Systems Biology Markup Language
The International Society for Systems Biology
Systems Biology Portal www.systems-biology.org
HepatoSys - Network Systems Biology
SystemsX - The Swiss Initiative in Systems Biology

Systems Biology Modeling Tools

Systems Biology WorkBench SWB package
JDesigner: A Biochemical Network Layout Tool
CADLIVE - network construction system
Dizzy stochastic simulations tool
CellDesigner - a modeling tool for biochemical networks
CellWare - building computational chassis for systems and synthetic biology
E-Cell project
COPASI - Complex Pathway Simulator
Gepasi - Biochemical Kinetics Simulator
JSim - a Java based simulation system
STOCKS - Stochastic kinetic simulations
JWS Online - Online Cellular Systems Modelling
PyBioS - web server for modeling and simulation of cellular systems
Virtual Cell Internet simulation server at NRCAM