PUBLIKATIONSVERZEICHNIS (PD Dr. Christian und Dr. Hella Bartsch)

 

a) wissenschaftliche Originalpublikationen (O):

 1. Bartsch C., Bartsch H., Jain A.K., Laumas K.R., Wetter­berg L. (1981) Urinary melatonin levels in human breast cancer patients. J. Neural Transm. 52, 281-294.

 2. Bartsch H., Bartsch C. (1981) Effect of melatonin on ex­perimental tumors under different photoperiods and times of administration. J. Neural Transm. 52, 269-279.

 3. Bartsch C., Bartsch H., Flüchter S.H., Harzmann R., Attanasio A., Bichler K.-H., Gupta D. (1983) Circadian rhythms of serum melatonin, prolactin and growth hormone in patients with benign and malignant tumors of the prostate and in non-tumor controls. Neuroendocrinol. Lett. 5, 377-386.

 4. Bartsch C., Bartsch H., Flüchter S.-H., Attanasio A., Gupta D. (1985) Evidence for modulation of melatonin secret­ion in men with benign and malig­nant tumors of the prostate: relationship with the pituitary hormones. J. Pineal Res. 2, 121-132.

 5. Bartsch H., Bartsch C., Flehmig B. (1986). Differential effect of melato­nin on slow and fast growing passages of a human melanoma cell line. Neuro­endocrinol. Lett. 8, 289-293.

 6. Bartsch H., Bartsch C., Noteborn H.P.J.M., Flehmig B., Ebels I., Sale­mink C.A. (1987) Growth-inhibiting effect of crude pineal extracts on human melanoma cells in vitro is different from that of known syn­thetic pineal substan­ces. J. Neural Transm. 69, 299-311.

 7. Noteborn H.P.J.M., Bartsch H., Bartsch C., Mans D.R.A., Weusten J.J.A.M., Flehmig B., Ebels I., Salemink C.A. (1988) Partial purifi­cation of (a) low molecular weight ovine pineal compound(s) with an inhibiting effect on the growth of human melanoma cells in vitro. J. Neural Transm. 73, 135-155.

 8. Bartsch C., Bartsch H., Fuchs U., Lippert T. H., Bell­mann O., Gupta D. (1989) Stage-dependent depression of melatonin in patients with pri­mary breast cancer: correla­tion with prolactin, TSH and steroid recep­tors. Cancer 64, 426-433.

 9. Noteborn H.P.J.M., Weusten J.J.A.M., Bartsch H., Bartsch C., Fleh­mig B., Ebels I., Salemink C.A. (1989) Partial purification of a polypeptide extract derived from ovine pineal that suppresses the growth of human melanoma cells in vitro. J. Pineal Res. 6, 385-396.

10. Bartsch C., Bartsch H., Lippert T.H., Gupta D. 1990) Effect of the mammary carcinogen 7,12-dimethyl­benz[a]anthrac­ene on pineal mela­tonin biosynthesis, secretion, and peripheral metabolism. Neuroendocrino­logy 52, 538-544. 

11. Bartsch H., Bartsch C., Gupta D. (1990) Tumor-inhibiting activity in the rat pineal gland displays a circannual rhythm. J. Pineal Res. 9, 171-178.

12. Bartsch C., Bartsch H., Bellmann O., Lippert T.H. (1991) Depression of serum melatonin in patients with primary breast cancer is not due to an increased peripheral metabolism. Cancer 67, 1681-1684.

13. Bartsch C., Bartsch H., Schmidt A., Ilg S., Bichler K.-H., Flüchter S.-H. (1992) Melatonin and 6-sulfatoxymelatonin circadian rhythms in serum and urine of primary  prostate cancer patients: evidence for reduced pineal activity and relevance of urinary determinations. Clin. Chim. Acta 209, 153-167.

14. Bartsch H., Bartsch C., Simon W.E., Flehmig B., Ebels I., Lippert T.H. (1992) Antitumor activity of the pineal gland: effect of unidenti­fied substances versus the effect of melatonin. Oncology 49, 27-30.

15. Bartsch C., Bartsch H., Flüchter St.-H., Mecke D., Lippert T.H. (1994) Diminished pineal function coincides with disturbed circadian endocrine rhythmicity in untreated primary cancer patients: consequence of premature aging or of tumor growth? Ann. N.Y. Acad. Sci. 719, 502-525.

16. Bartsch H., Bartsch C., Mecke D., Lippert T.H. (1994) Seasonality of pineal melatonin production in the rat: possible synchronization by the geomagnetic field. Chronobiol. Int. 11, 21-26.

17. Karasek M., Marek K., Zielinska A., Swietoslawski J., Bartsch H., Bartsch C. (1994) Serial transplants of 7,12-dimethylbenz[a]anthracene-induced mammary tumors in Fischer rats as model system for human breast cancer: 3. Quantitative ultrastructural studies of the pinealocytes and plasma melatonin concentrations in rats bearing an advanced passage of the tumor. Biol. Signals 3, 302-306.

18. Anisimov V.N., Zhukova O.V., Labunets I.F., Bartsch H., Bartsch C.(1995) The inhibitory effect of light deprivation on N-nitrosomethylurea-induced carcino­genesis and on the growth of transplanted tumors in rodents: possible in­volvement of the pineal gland and the immune system. Exp. Oncology 17, 47-54­.

19. Bartsch C. (1995) Letter to the Editor (Hepatic hydroxylation of melatonin in the rat is induced by phenobarbital and 7,12-dimethylbenz[a]anthracene - implications for cancer etiology.) Experientia 51, 1000-1001.

20. Bartsch C., Bartsch H., Buchberger A., Rokos H., Mecke D., Lippert T.H. (1995) Serial transplants of DMBA-induced mammary tumors in Fischer rats as model system for human breast cancer: IV. Parallel changes of biopterin and melatonin indicate interactions between the pineal gland and cellular immunity in malignancy. Oncology 52, 278-283.

21. Bartsch C., Seeger H., Mück A.O., Lippert T.H. (1995) The effect of estradiol on the production of melatonin in postmenopausal women. Int. J. Clin. Pharm. Ther. 33, 401-403.

22. Praast G., Bartsch C., Bartsch H., Mecke D., Lippert T.H. (1995) Hepatic hydroxylation of melatonin in the rat is induced by phenobarbital and 7,12-dimethylbenz[a]anthracene - implications for cancer etiology. Experientia 51, 349-355.

23. Bartsch C., Bartsch H. (1996) Letter to the editor. J. Pineal Res. 20, 173.

24. Karasek M., Dec W., Kowalski A.J., Bartsch H., Bartsch C. (1996) Serum melatonin circadian profile in women with adenocarcinoma of uterine corpus. Int. J. Thymology 4 (Suppl. 1), 80-83.

25. Mück A.O., Seeger H., Bartsch C., Lippert T.H. (1996) Does melatonin affect calcium influx in human aortic smooth muscle cells and estradiol-mediated calcium antagonism? J. Pineal Res. 20, 145-147.

26. Bartsch C., Bartsch H., Karenovics A., Franz H., Peiker G., Mecke D. (1997) Nocturnal urinary 6-sulphatoxymelatonin excretion is decreased in primary breast cancer patients compared to age-matched controls and shows negative correlation with tumor-size. J. Pineal Res. 23, 53-58.

27. Bartsch C., Kvetnoy I., Kvetnaia T., Bartsch H., Molotkov A., Franz H., Raikhlin N., Mecke D. (1997) Nocturnal urinary 6-sulfatoxymelatonin and proliferating cell nuclear antigen-immunopositive tumor cells show strong positive correlations in patients with gastrointestinal and lung cancer. J. Pineal Res. 23, 90-96.

28. Bartsch C., Bartsch H., Bichler K.-H., Flüchter St.-H. (1998) Prostate cancer and tumor stage-dependent circadian neuroendocrine disturbances. The Aging Male 1, 188-199.

29. Hoffmann H., Dittgen M., Hoffmann A., Bartsch C., Breitbarth H., Timpe C., Farker K., Schmidt U., Mellinger U., Zimmermann H., Gräser T., Oettel M. (1998) Evaluation of an oral pulsatile delivery system for melatonin in humans. Pharmazie 53, 462-466.

30. Körner W., Hanf V., Schuller W., Bartsch H., Zwirner M., Hagenmaier H. (1998) Validation and application of a rapid in vitro assay for assessing the estrogenic potency of halogenated phenolic chemicals. Chemosphere 37, 2395-2407.

31. Müller W.A., Bartsch C., Bartsch H., Maidonis I., Bayer E. (1998) Hormonal factors from the mammalian pineal gland interfere with cell development in Hydra. Int. J. Dev. Biol. 42, 821-824.

32. Müller W.A., Bartsch C., Bartsch H., Maidonis I., Bayer E. (1998) Low-molecular-weight hormonal factors that affect head formation in Hydra. Int. J. Dev. Biol. 42, 825-828.

33. Anisimov V.N., Kvetnoy I.M., Chumakova N.K., Kvetnaya T.V., Molotkov A.O., Pogudina N.A., Popovich I.G., Popuchiev V.V., Zabezhinski M.A., Bartsch H., Bartsch C. (1999) Melatonin and colon carcinogenesis. II. Intestinal melatonin-containing cells and serum melatonin level in rats with 1,2-dimethylhydrazine-induced colon tumors. Exp. Toxic. Pathol. 51, 47-52.

34. Bartsch C., Bartsch H., Buchberger A., Stieglitz A., Effenberger-Klein A., Kruse-Jarres J.D., Besenthal I., Rokos H., Mecke D. (1999) Serial transplants of DMBA-induced mammary tumors in Fischer rats as a model system for human breast cancer. VI. The role of different forms of tumor-associated stress for the regulation of pineal melatonin secretion. Oncology 56, 169-176.

35. Bartsch C., Szadowska A., Karasek M., Bartsch H., Geppert M., Mecke D. (2000) Serial transplants of DMBA-induced mammary tumors in Fischer rats as model system for human breast cancer: V. Myoepithelial-mesenchymal conversion during passaging as possible cause for modulation of pineal-tumor interaction. Exp. Toxic. Pathol. 52, 93-101.

36. Bartsch H., Buchberger A., Franz F., Bartsch C., Maidonis I., Mecke D., Bayer E. (2000)  Effect of melatonin and pineal extracts on human ovarian and mammary tumor cells in a chemosensitivity assay. Life Sci. 67, 2953-2960.

37. Cos S, Alvarez A., Mediavilla M.D., Bartsch C., Bartsch H., Sanchez-Barcelo E.J. (2000) Influence of serum from healthy or breast tumor-bearing women on the growth of MCF-7 human breast cancer cells. Int. J. Mol. Med. 5, 651-656.

38. Bartsch H., Bartsch C., Deerberg F., Mecke D. (2001) Seasonal rhythms of 6-sulphatoxymelatonin (aMT6s) excretion in female rats are abolished by growth of malignant tumors. J. Pineal Res. 31, 57-61.

39. Bartsch H., Bartsch C., Seebald E., Deerberg F. Dietz K., Vollrath L., Mecke D. (2002) Chronic exposure to a GSM-like signal (mobile phone) does not stimulate the development of DMBA-induced mammary tumors in rats: results of three consecutive studies. Rad. Res. 157, 183-190.

40. Girgert R., Bartsch C., Hill S.M., Kreienberg R., Hanf, V. (2003) Tracking the elusive antiestrogenic effect of melatonin: a new methodological approach. Neuroendocrinology Lett. 24, 440-4.

41. Bartsch C., Bartsch H. (2006) The anti-tumor activity of pineal melatonin and cancer enhancing life styles in industrialized societies. Cancer Causes Control 17,559-571.

 42. Kröz M., Zerm R., Reif M., von Laue H.B., Schad F., Büssing A., Bartsch C., Feder G., Girke M. (2007) Validation of the German version of Cancer Fatigue Scale (CFS-D). European J Cancer Care, 1-9.

 43. Bartsch C. (2010) Light-at-night, cancer and aging.Aging (Albany NY), 2(2), 76-77.

 44. Bartsch H., Küpper H. Scheurlen u, Deerberg F., Seebald E, Dietz K., Mecke D. Probst H., Stehle T., Bartsch C. (2010) Effect of chronic exposure to a GSM-like signal (mobile phone) on survival of female Sprague-Dawley rats: modulatory effects by month of birth and possibly stage of the solar cycle. Neuro Endocrinol. Lett. 31(4), 457-473.

 45. Bartsch H., Mecke D., Probst H., Küpper H., Seebald E., Salewski, Stehle T., Bartsch C. Search for seasoanl rhythmicity of pineal melatonin in rats under constant laboratory conditions: spectral chronobiological analysis, and relation to solar and geomagnetic variables. (2012) Chronobiol. Int. 29(8), 1048-1061.

 46. Bartsch  H., Mecke D., Probst H., Küpper H., Seebald E., Herget I., Peschke E., Salewski, Stehle T., Bartsch C. Longitudinal melatonin production in female laboratory rats during 1997-2006: possible modulatory effects of changing solar activity. Current Aging Sci. (Suppl.)., in press. 

  

b) Fort-/Weiterbildung bzw. Übersichtsartikel (F):

 1. Bartsch C., Bartsch H., Lippert T.H. (1991) Bedeutung der Zirbel­drüse bei Reproduktion und gynäkologi­schen Tumoren. Geburtsh. u. Frauenheil­k. 51, 1-8.

 2. Bartsch H., Bartsch C., Lippert T.H. (1991) Melatonin und chronobiolo­gische Aspekte von Krebs. Münch. med. Wschr. 133, 113-116.

 3. Bartsch C., Bartsch H., Lippert T.H. (1992) The pineal gland and cancer: facts, hypotheses and perspectives. Cancer J. 5, 194-199. 

 4. Bartsch C., Bartsch H., Lippert T.H. (1995) Rationales to consider the use of melatonin as a chrono-oncotherapeutic drug. In vivo 9, 305-310.

 5. Bartsch H. (1995) Biologische Rhythmen – Bedeutung für Schwangerschaft, Geburt und das Neugeborene. Dtsch. Heb. Zschr. 1/95, 3-6.

 6. Bartsch C., Bartsch H. (1997) Die Bedeutung des Melatonins bei malignen Erkrankungen. Wien. Klin. Wschr. 109, 722-729.

 7. Bartsch C., Bartsch H. (1997) Pineal gland and cancer: An old concept with potential for the future. Neuroendocrinol Lett. 18, 63-72.

 8. Bartsch C., Bartsch H., Karasek M. (2002) Melatonin in clinical oncology. Neuroendocrinol. Lett. 23 (Suppl. 1), 30-38.

 9. Bartsch C., Bartsch H. (2007) Die Bedeutung des Melatonins in der Wechselbeziehung zwischen Zirbeldrüse und Krebs – eine Übersicht mit neuen Resultaten. Abhandlungen der Sächsischen Akademie der Wissenschaften zu Leipzig – Mathematisch-naturwissenschaftliche Klasse, Bd. 64 Heft 4: Endokrinologie III. E. Peschke (Ed.), Hirzel, Stuttgart/Leipzig, 139-174.

 10. Bartsch C., Bartsch H., Peschke E. (2009) Light. melatonin and cancer: current results and future perspectives. Biol. Rhythm Res. 40, 17-35. 

  

c) Zitierbare Abstracts (A):

 1. Bartsch C., Bartsch H., Flüchter St. H., Harzmann R., Bichler K.-H., Gupta D. (1982) Serum melatonin and cortisol rhythms of patients with benign and malignant tumours of the prostate. Neuroendocrinol. Lett. 4, 176.

 2. Bartsch C., Bartsch H. (1985) The biochemical events in the pineal gland during development. Neuroendocrinol. Lett. 7, 152.

 3. Bartsch C., Bartsch H., Flüchter St.-H., Attanasio A., Gupta D. (1986) Melatonin rhythms in prostate cancer patients: effect of operation and hormone treatment. J. Neural Transm. Suppl. 21, 491.

4. Bartsch H., Bartsch C., Flehmig B. (1986) Effect of melatonin on human melanoma cells in vitro. J. Neural Transm. Suppl. 21, 490.

5. Flüchter S.H., Bartsch C., Bartsch H., Attanasio A. (1986) Pineal melatonin and pituitary hormone rhythms in patients with prostatic cancer and in controls. Urolog. Res. 14, 165.

6. Bartsch C., Bartsch H. (1987) Melatonin rhythms in human cancer patients. Neuroendocrinol. Lett. 9, 306.

7. Bartsch H., Bartsch C. (1987) Unidentified pineal substances with anti-tumor activity. Neuroendocrinol. Lett. 9, 307.

8. Ebels I., Noteborn H.P.J.M., Bartsch H., Bartsch C. (1987) Effects of low molecular weight pineal compounds on neoplastic growth. Neuroendocrinol. Lett. 9, 288.

9. Bartsch C., Bartsch H., Gupta D. (1989) Effect of induction and growth of mammary tumors on pineal melatonin biosynthesis and secretion in female Sprague-Dawley rats. Neuroendocrinol. Lett. 11, 280.

10. Bartsch H., Bartsch C., Gupta D. (1989) Seasonal variations of endogenous defence mechanisms against cancer. Neuroendocrinol. Lett. 11, 281.

11. Bartsch C., Bartsch H., Lippert T.H. (1994) Pineal melatonin secretion in human cancer patients and interaction with other endocrine glands. In: Proceedings of the International Conference on Melatonin: General Biological and Oncoradiological Aspects. I.M. Kvetnoy, R.J. Reiter (eds.), Medical Radiological Research Center, Obninsk, Russia, 8.

12. Bartsch H., Bartsch C. (1994) Anti-tumor activity of the pineal gland: melatonin and beyond. In: Proceedings of the International Conference on Melatonin: General Biological and Oncoradiological Aspects. I.M. Kvetnoy, R.J. Reiter (eds.), Medical Radiological Research Center, Obninsk, Russia, 26-27.

13. Drozdovskiy B.J., Garbuzov P.I., Kvetnaia T.V., Bartsch C., Bartsch H. (1994) Nocturnal 6-sulphatoxymelatonin secretion in patients with benign and malignant tumors of the thyroid gland and non-tumor controls (preliminary report) In: Proceedings of the International Conference on Melatonin: General Biological and Oncological Aspects, I.M. Kvetnoy, R.J. Reiter (eds.). Medical Radiological Research Center, Obninsk, Russia, 47.

14. Medvedev V.N., Garbuzov P.I., Kvetnaia T.V., Bartsch C., Bartsch H., Raikhlin N.T., Perevoschikov A.G., Davydov M.I., Stilidi I.S., Timofeev Y.M. (1994) Changes of nocturnal excretion of 6-sulphatoxymelatonin in patients with lung and stomach malignant tumors after operation (preliminary report) In: Proceedings of the International Conference on Melatonin: General Biological and Oncological Aspects, I.M. Kvetnoy, R.J. Reiter (eds.). Medical Radiological Research Center, Obninsk, Russia, 77-78.

15. Bartsch C., Bartsch H., Flüchter St.-H., Lippert T.H. (1995) Tumor-stage dependent depression of the circadian amplitude of melatonin in patients with unoperated primary breast and prostate cancer is connected with disturbances in the secretion of prolactin, TSH and growth hormone. The Physiologist 38, A-32.

16. Bartsch H., Bartsch C., Deerberg F., Mecke D., Lippert T.H. (1995) Circannual rhythms of pineal melatonin production in female rats are abolished by growth of malignant tumors. The Physiologist 38, A-27.

17. Seeger H., Mück A.O., Bartsch C., Lippert T.H. (1995) Effect of melatonin on depolarized human aortic smooth muscle cells. Menopause 2, 261-262 (P32).

18. Bartsch C., Bartsch H., Rokos H. (1996) Neopterin and melatonin levels in patients with benign hyperplasia or carcinoma of the prostate. Pteridines 7, 41.

19. Kvetnoy I., Bartsch C., Bartsch H., Kvetnaia T., Medvedev V., Raikhlin N. (1996) Melatonin and proliferative activity of tumours: successful combination of immunohistochemical and radioimmunological methods for definition of prognosis in humans. Acta Histochem. Cytochem. (Japan) 29 (Suppl.), 304-305.

20. Bartsch C. (1997) Modulation of diurnal pineal melatonin secretion in cancer patients depending on type and stage of malignant disease. Cancer Biotherapy 12, 413.

21. Bartsch C. (1997) Synergistic modulation of melatonin and immune parameters in rats with serial transplants of experimental mammary tumors are accompanied by differential reactions of the autonomic nervous system. Cancer Biotherapy 12, 413-414.

22. Bartsch H., Bartsch C., Mecke D. (1997) Lack of effect of a chronic three-week exposure to a pulsed high-frequency electromagnetic field on the diurnal urinary excretion of 6-sulfatoxymelatonin in male CD-rats. Cancer Biotherapy 12, 414-415.

23. Buchberger A., Maidonis I., Bartsch H., Bartsch C., Franz H., Bayer E. (1997) Effect of the pineal extract YC05R and melatonin on human primary ovarian and mammary tumor cells. Cancer Biotherapy 12, 416.

24. Deerberg F., Bartsch C., Pohlmeyer G., Bartsch H. (1997) Effect of melatonin and physiological epiphysectomy on the development of spontaneous endometrial carcinoma in BDII/Han rats. Cancer Biotherapy 12, 420.

25. Kvetnaia T.V., Kvetnoy I.M., Bartsch C., Bartsch H., Raikhlin N.T. (1997) Melatonin and proliferative activity of tumour cells. Proc. Royal Microscop. Soc. 32 (Suppl. 2), 50.

26. Kvetnoy I., Yuzhakov V., Bartsch C., Bartsch H., Kvetnaia T. (1997) Potential role of melatonin in the control of non-endocrine human and experimental tumors. Cancer Biotherapy 12, 425.

 27. Schmidt U., Bartsch C., Bartsch H., Mecke D. (1997) Pineal melatonin secretion seems to be reversibly inhibited by a tumor-derived melatonin inhibiting factor. Cancer Biotherapy 12, 429.

 28. Bartsch C., Bartsch H., Mecke D. (1999) Neuroimmunoendocrine mechanisms involved in the modulation of circulating melatonin in breast cancer patients. Neuroimmunomodulation 6, 410.

 29. Bartsch H., Bartsch C. (1999) The effects of melatonin and constant light on the development of spontaneous endometrial carcinomas in aging BDII/Han rats appear to be exerted by modulating maturation of the reproductive system. Zschr. Gerontol. Ger. 32 (Suppl. 2), 12.

30. Bartsch C., Bartsch H., Mecke D. (2000) Melatonin and cancer: experimental and clinical aspects. Zbl. Arbeitsmed. 50, 304-305.

31. Mück A.O., Bartsch C. (2003) Melatonin und Jetlag: Physiologische Grundlagen für eine Jetlag-vermindernde Wirkung des Melatonins. Geburtsh. u. Frauenheil­k. (Im Druck).

32. Bartsch C., Bartsch H. (2005) Current understanding of the role of melatonin in malignancy. Chronobiol Int. 22, 1305-1306.

 

d). Bücher/Buchbeiträge (B):

1. Bartsch C., Bartsch H. (1984) The link between the pineal gland and can­cer: an interaction involving chronobiological mechanisms. In: Chronobiolog­ical Approach to Social Medic­ine, F. Halberg, L. Reale, B. Tarquini (Eds.), Istituto Ital­iano di Medicina Sociale, Rom, 105-126.

2. Bartsch H., Bartsch C., Flehmig B. (1987) Pineal anti-tumor activity (PATA) of rats under different physiological conditions. In: Fundament­als and Clinics in Pineal Re­search, G.P. Trentini, C. DeGaetani, P. Pévet (Eds.), Raven Press, New York, 381-384.

3. Bartsch C., Bartsch H. (1988) Melatonin in human cancer pat­ients. In: The Pineal Gland and Cancer, D. Gupta, A. Atta­nasio, R.J. Reiter (Eds.), Brain Research Promotion, Lon­don, 361-368.

4. Bartsch H., Bartsch C. (1988) Unidentified pineal sub­stan­ces with anti-tumor activity. In: The Pineal Gland and Cancer, D. Gupta, A. Attanasio, R.J. Reiter (Eds.), Brain Research Promotion, London, 369-376.

5. Ebels I., Noteborn H.P.J.M., Bartsch H., Bartsch C. (1988) Effects of low molecular weight pineal compounds on neoplastic growth. In: The Pineal Gland and Cancer, D. Gupta, A. Attanasio, R.J. Reiter (Eds.), Brain Research Pro­motion, London, 261-272.

 6. Bartsch C., Bartsch H., Gupta D. (1990) Pineal melatonin synthesis and secretion during induction and growth of mammary cancer in female rats. In: Neuroendocrinology: New Frontiers. D. Gupta, H.A. Wollmann, M.B. Ranke (Eds.), Brain Research Promotion, London: Tübingen, 325-332.

 7. Bartsch H., Bartsch C., Gupta D. (1990) Seasonal variations of endo­gen­ous defence mechanisms against cancer. In: Neuroendocrinology: New Front­iers. D. Gupta, H.A. Wollmann, M.B. Ranke (Eds.), Brain Research Promot­ion, London: Tübingen, 333-339.

 8. Kvetnoy I.M., Kvetnaja T., Bartsch H., Bartsch C. (1992) Melatonin: sums and per­spectives of the study in oncology (In Russisch). In: Regulatory Peptides and Biogenic Amines: Radiobiological and Oncoradiological Aspects. A.F. Cyb, I.M. Kvetnoy (Eds.), Institute of Medical Radiology, Obninsk, Russia, 29-34.

 9. Bartsch C., Bartsch H. (1993) Endocrine rhythms in patients with breast and prostate cancer. In: Chronobiology and Chronomedicine: Basic Research and Applications. C. Gutenbrunner, G. Hildebrandt, R. Moog (Eds.), Peter Lang-Verlag, Frankfurt, 405-410.

10. Bartsch C., Bartsch H., Flüchter St. H., Lippert T.H. (1993) Depleted pineal melatonin production in patients with primary breast and prostate cancer is connected with circadian disturbances of central hormones: possible role of melatonin for maintenance and synchronizat­ion of circadian rhythmicity. In: Melatonin and the pineal gland - from basic science to clinical applications. Y. Touitou, J. Arendt, P. Pevet (Eds.), Elsevier, Amsterdam, 311-316.

11. Bartsch C., Praast G., Peters C., Bartsch H., Mecke D., Lippert T.H. (1993) The hepatic metabolism of melatonin in the rat: phenobarbital and polyaromatic hydrocarbons are inducers of the hydroxylation of mela­tonin. In: Melatonin and the pineal gland - from basic science to clinical applications. Y. Touitou, J. Arendt, P. Pevet (Eds.), Elsevier, Amsterdam, 317-320.

12. Bartsch H., Bartsch C. (1993) Anti-tumor activity in pineal glands and in urine display similar circannual rhythmicity. In: Chronobiology and Chronomedicine: Basic Research and Applications. C. Gutenbrunner, G. Hildebrandt, R. Moog (Eds.), Peter Lang-Verlag, Frankfurt, 390-395.

 13. Bartsch H., Bartsch C., Mecke D., Lippert T.H. (1993) The relationship between the pineal gland and cancer: seasonal aspects. In: Light and Biological Rhythms. L. Wetterberg (Ed). Pergamon Press, Oxford, 337-347.

14. Bartsch C., Bartsch H. (1994) Melatonin secretion in oncological patients: current results and methodological considerations. In: Adv. Pineal Res., Vol. 7, G.J.M. Maestroni, A. Conti, R.J. Reiter (Eds.), John Libbey, London, 283-301.

 15. Bartsch C., Bartsch H., Buchberger A., Stieglitz A., Mecke D., Lippert T.H. (1994) Serial transplants of DMBA-induced mammary tumors in Fischer rats as model system for human breast cancer: II. Analysis of pineal melatonin biosynthesis and secretion. In: Adv. Pineal Res., Vol. 8, M. Mφller, P. Pévet (Eds.), John Libbey, London, 479-484.

 16. Bartsch H., Bartsch C., Mecke D., Lippert T.H. (1994) Differential effect of melatonin on early and advanced passages of a DMBA-induced mammary carcinoma in the female rat. In: Adv. Pineal Res., Vol. 7, G.J.M. Maestroni, A. Conti, R.J. Reiter (Eds.), John Libbey, London, 247-252.

 17. Bartsch H., Bartsch C., Mecke D., Lippert T.H. (1994) Serial transplants of DMBA-induced mammary tumors in Fischer rats as model system for human breast cancer: I. Effect of melatonin and pineal extracts on  slow- and fast-growing passages  -  in vivo and in vitro studies. In: Adv. Pineal Res., Vol. 8, M. Mφller, P. Pévet (Eds.), John Libbey, London, 473-478.

18. Garbuzov P.I., Drozdovsky B.Y., Kvetnaia T.V., Bartsch C., Bartsch H., Lippert T.H., Raikhlin N.T., Medvedev V.N., Kvetnoy I.M., Perevoshikov A.G., Davydov M.I., Stilidi I.S., Timofeev Y.M. (1995) Diagnostic and prognostic aspects of the study of nocturnal excretion of 6-sulphatoxymelatonin in cancer patients (In Russisch). In: The Surgery of Endocrine Glands. A.P. Kalinin and V.M. Trofimov (Eds.) St. Petersburg Medical Publication Company, Russia, 40-43.

19. Bartsch C., Bartsch H. (1997) Modulation of melatonin secretion in cancer patients: possible mechanisms and significance for prognosis, diagnosis and treatment. In:  Therapeutic potential of melatonin. G.J.M. Maestroni, A. Conti, R.J. Reiter (Eds.), Front. Hormon. Res. Vol. 23, Karger, Basel, 115-124.

20. Bartsch C., Bartsch H. (1997) The modulation of pineal melatonin secretion in malignancy: results and possible mechanisms. In: Pineal update: molecular mechanisms to clinical implications. S.M. Webb, M. Puig-Domingo (Eds.), PJD Publications, Westbury NY, 369-376.

21.Bartsch C., Bartsch H. (1999) Melatonin in cancer patients and in tumor-bearing animals. In: Trypophan, Serotonin, and Melatonin: Basic Aspects and Applications, Adv. Exp. Biol. Vol. 467. G. Huether, W. Kochen, T. Simat (Eds.), Kluwer Academic, New York, 247-264.

22. Bartsch C., Bartsch H., Blask D.E., Cardinali D.P., Hrushesky W.J.M., Mecke D. (2001) The pineal gland and cancer: neuroimmunoendocrine mechanisms in malignancy. Springer-Verlag, Heidelberg (578 Seiten).

23. Bartsch C., Bartsch H., Mecke D. (2001) Analysis of melatonin in patients with cancer of the reproductive system. In: The pineal gland and cancer: neuroimmunoendocrine mechanisms in malignancy. C. Bartsch, H. Bartsch, D.E. Blask, D.P. Cardinali, W.J.M. Hrushesky (Eds.), Springer-Verlag, Heidelberg, 153-176.

 24. Bartsch H., Bartsch C., Mecke D. (2001) The modulation of melatonin in tumor-bearing animals: underlying mechanisms and possible significance for prognosis. In: The pineal gland and cancer: neuroimmunoendocrine mechanisms in malignancy. C. Bartsch, H. Bartsch, D.E. Blask, D.P. Cardinali, W.J.M. Hrushesky (Eds.), Springer-Verlag, Heidelberg, 197-209.

25. Kvetnaia T.V., Kvetnoy I.M., Bartsch H., Bartsch C., Mecke D. (2001) Melatonin in patients with cancer of extra-reproductive location. In: The pineal gland and cancer: neuroimmunoendocrine mechanisms in malignancy. C. Bartsch, H. Bartsch, D.E. Blask, D.P. Cardinali, W.J.M. Hrushesky (Eds.), Springer-Verlag, Heidelberg, 177-196.

26. Bartsch C. Bartsch H. (2005) Chronobiologie: Rhythmen des Lebens. In: Rhythmen in den Künsten und Wissenschaften. B. Naumann (Ed.), Wilhelm Fink Verlag, Paderborn, 15-48.

27. Bartsch C., Bartsch H. (2006) Pineal gland and cancer – an epigenetic approach to the control of malignancy: evaluation of the role of melatonin. In: Melatonin: biological basis of its function in health and disease. S. R. Pandi-Perumal, D. P. Cardinali (Eds.), M/S Landes Bioscience, Georgetown, Tx. 71-87.

Sowie:http://www.ncbi.nlm.nih.gov/books/bv.fcgi?call=bv.View..ShowSection&rid=eurekah.chapter.22797

28. The anti-tumor activity of the pineal gland and cancer enhancing life styles in industrialized societies: melatonin and beyond. In: Rhythm disturbances and cancer. M. Moser and A. Ertl (Eds.) Springer-Verlag, Heidelberg, in press.